Home-based remote monitoring for Covid reduced hospitalizations, hospital length of stay: JAMA study

July 15, 2022 | by

Activation of remote patient monitoring (RPM) in this study is associated with lower hospitalization, intensive care use, and if hospitalized, length of stay. Conducted by Froedtert & Medical College of Wisconsin Health Network with Covid-19 positive ambulatory patients who accepted RPM in the home (N=9,378), the study’s purpose was to evaluate the implementation of a large-scale daily RPM program for patients who were managing symptoms from home. They compared those who activated their RPM (N=5,364, 57%) versus those who did not (N=4,014, 43%). The mean age was 46 and 58% were women.

  • 878 patients  (16.4%) had at least one RPM alert
  • 2.4% (128) of the activated patients were hospitalized, compared to 3.9% (158) of inactivated patients

A weighted regression analysis, adjusted for demographics, comorbidities, and time period, compared RPM-activated to the tracked but inactivated patients:

  • Lower odds of hospitalization (odds ratio, 0.68; 95% CI, 0.54-0.86; P = .001)
  • Greater time between test and hospitalization for RPM-activated patients 6.67 [3.21] days vs 5.24 [3.03] days)
  • Shorter length of stay (4.44 [4.43] days vs 7.14 [8.63] days)
  • Less intensive care use (15 patients [0.3%] vs 44 patients [1.1%])

The study excluded patients younger than 18 years, those with asymptomatic tests (because these were often scheduled before procedures or other planned admissions), patients who were admitted within 24 hours of a positive test, and those who already had internal PCPs to reduce the chance of missing hospitalizations. The RPM provider was GetWellNetwork using the GetWellLoop monitored by a centralized team of Froedtert & Medical College of Wisconsin nurses. Patients used the web or a mobile app to record their symptoms, temperatures, and pulse oximetry readings. Hospitalization Outcomes Among Patients With COVID-19 Undergoing Remote Monitoring (abstract and downloadable PDF)

Funding, acquisition news roundup, round 2: Lyra Health’s $187M Series E, DarioHealth-Upright, GetWellNetwork-Docent Health, Hillrom-BardyDx (updated)

January 29, 2021 | by

Our cowgirl has been keeping busy rounding up more news on funding and acquisitions. Significance? Nearly all are major rounds only dreamed of a year ago for these relatively small companies boosting valuations into the stratosphere. The acquisitions also extend these companies into multiple lines of business.

Lyra Health, a mental health therapy benefit company for employers, closed an additional $187 million in a Series E round led by Addition Capital. This adds to a torrid 2020 $185 million Series C and D bringing their total funding to $475 million. The company claims a valuation of $2.3 billion and doubling its customer base in 2020 to 2 million members, with marquee clients such as Genentech, Morgan Stanley, and Zoom. Lyra Health uses cognitive-based therapy (CBT) models using virtual self-care, coaching, and therapists. Also announced was a partnership with ICAS World, an employee-assistance provider. Lyra is one of many companies in an increasingly crowded category using the CBT model to save employers and payers money on employee and member mental health with and without chronic conditions such as diabetes. Earlier this month, the Talkspace app, which focuses on direct to consumer therapy, announced they were going public through a ‘blank check’ SPAC with Hudson Executive Investment Corp, in a deal valued at $1.4 billion, including debt. Release, Mobihealthnews

DarioHealth, an Israeli-US company concentrating on digital diabetes and hypertension management, extended into musculoskeletal (MSK) therapeutics with the $31 million acquisition of Upright Technologies Ltd., another Israeli-US company. Upright uses a $100 sensor that provides biofeedback and vibration reminders to correct posture plus digital coaching. Last year, Upright was heavily advertised on US television. The buy will transfer to Upright $1.5 million in cash and $29.5 million in stock, and is expected to close in about 10 days. Dario also completed a $70 million private placement for 3,278,688 shares of its common stock at a purchase price of $21.35 per share. Dario has about 150,000 users and Upright 90,000 users. Dario is projecting a 2020 revenue of $7.6 million. Release, Mobihealthnews

GetWellNetwork, a relatively small player in patient engagement and communications in the inpatient care journey, announced it has acquired patient-messaging company Docent Health for an undisclosed sum, beefing up capabilities in data analytics and directing patients to additional services. According to Crunchbase, GetWellNetwork has funding to date of $19 million.  Release, Mobihealthnews

Wrapping it up is cardiac monitoring giant Hillrom’s acquisition of Bardy Diagnostics for $375 million plus future potential payments based on the achievement of certain commercial milestones. Hillrom is also acquiring net operating losses valued at more than $20 million and 230 employees. The BardyDx Carnation Ambulatory Monitor (CAM) is a lightweight cardiac patch monitor for heart rhythm diagnostics using P-wave-centric ECG detection. The irony here is that BardyDx positioned itself squarely against Hillrom’s Holter monitors. Nothing like buying out the competition! Release, MedCityNews