Early detection of Parkinson’s via AI (and a surprising medium); Ed Marx on the digital transformation (or not) of health systems and COVID treatment at home

Somewhat off our normal beat….but of interest.

Ardigen and The BioCollective are collaborating on early detection research for Parkinson’s Disease, based on a microbiome-based biomarker. Ardigen has developed an Artificial Intelligence (AI) Microbiome Translational Platform. The BioCollective has a bank of metagenomic and patient metadata generated from an unexpected source: Parkinson’s patients’ stool samples. Release

The BioCollective is headed by Martha Carlin, who came from well outside of healthcare and pulled together a research group to address her husband’s diagnosis. A visit to this website is worth an examination on how these samples are collected for microbiome extraction. An interesting twist is the marketing of a probiotic mix developed using their BioFlux metabolic model for ‘gut health’.

Ed Marx, the former CIO of the Cleveland Clinic, has written a new book, ‘Healthcare Digital Transformation: How Consumerism, Technology, and the Pandemic are Accelerating the Future’. It’s billed as a wake-up call for healthcare systems and hospitals under challenge by Big Retail, Big Pharma, and Big Tech. This Editor met Mr. Marx when he premiered his entertaining memoir, ‘Extraordinary Tales from a Rather Ordinary Guy’, a few years ago. On treatment for COVID patients, except for the very sickest, he advocates it being done from home. From the release: “When the pandemic hit, a lot of progressive organizations would send most of their Covid patients home with monitoring equipment hooked up to phones unless they needed a ventilator. It’s a lot cheaper than staying in the hospital.”

Dermal patch senses, releases meds as needed

[grow_thumb image=”https://telecareaware.com/wp-content/uploads/2014/04/nnano.2014.38-f1.jpg” thumb_width=”175″ /]A research team from several institutions in South Korea and University of Texas, Austin have developed a dermal patch that not only delivers medication, but in the right dose and right time based upon muscle activity and body temperature. They developed a 2-inch rectangle made of stretchable nanomaterials containing heat-activated silica nanoparticles. The patch monitors muscle activity and body temperature, then releases a controlled dose of a drug. This would make it ideal for conditions such as Parkinson’s Disease where the drug should be timed when muscle tremors begin. At this point, there is no digital health/wireless component for recording, which is also needed. But given the long lead time–it won’t be ready for sale for five years. The Verge. Nature Nanotechnology (abstract only)